Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | BAD | Q92934 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688186 | 0.85 | TP53 (0.47) | CES2CES1CA1CA2KMT2A | |
| SCHEMBL8572071 | 0.77 | LTA4H (0.73) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL1736339 | 0.77 | LTA4H (0.73) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL238259 | 0.77 | LTA4H (0.73) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL9769554 | 0.77 | RAB9A (0.46) | PTPN1BCL2L1BADNPC1RAB9A | |
| SCHEMBL716295 | 0.77 | CES2 (1.00) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL9173480 | 0.77 | SRD5A2 (0.55) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2287134 | 0.76 | MAOA (0.68) | CES2CES1PTPN1RAB9AMEN1 | |
| SCHEMBL5127523 | 0.76 | MEN1 (0.59) | CES2CES1CA1CA2PTPN1 | |
| SCHEMBL10368983 | 0.75 | CES2 (0.65) | CES2CES1CA1CA2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119798229-A | Preparation method of imatinib dimer | 中国食品药品检定研究院 | 2025-04-11 | — | — | CN | claimed |
| CN-119613413-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-116023242-A | Preparation method of aromatic dihalogen substituted compound, aromatic dihalogen substituted compound and application | 中国科学院大连化学物理研究所 | 2023-04-28 | — | — | CN | claimed |
| US-9974992-B2 | Fire extinguishing composition comprising carboxylic acid derivative | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-05-22 | — | — | US | claimed |
| EP-3095488-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING CARBOXYLIC ACID DERIVATIVE | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| US-20160332015-A1 | Fire Extinguishing Composition Comprising Carboxylic Acid Derivative | NANO FIRE, LLC | 2016-11-17 | — | — | US | claimed |
| CN-119798229-A | Preparation method of imatinib dimer | 中国食品药品检定研究院 | 2025-04-11 | — | — | CN | disclosed |
| CN-119613414-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119613413-A | Non-azolanet Process for the preparation of tam | 上海皓元医药股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-118930444-A | Fluorophenyl beta-hydroxyethylamine and its use in the treatment of hyperglycaemia | 阿托基公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-111148731-B | Fluorophenyl beta-hydroxyethylamine and its use in the treatment of hyperglycaemia | 阿托基公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116023242-A | Preparation method of aromatic dihalogen substituted compound, aromatic dihalogen substituted compound and application | 中国科学院大连化学物理研究所 | 2023-04-28 | — | — | CN | disclosed |
| CN-111148731-A | Fluorophenyl β -hydroxyethylamine and use thereof in the treatment of hyperglycaemia | 阿托基公司 | 2020-05-12 | — | — | CN | disclosed |
| EP-1219607-A1 | INTEGRASE INHIBITORS CONTAINING AROMATIC HETEROCYCLE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-07-03 | — | — | EP | disclosed |
| CN-1335834-A | Aromatic heterocyclic compounds having HIV integrase inhibitory activity | SHIONOGI & CO (JP) | 2002-02-13 | — | — | CN | disclosed |
| EP-1142872-A1 | AROMATIC HETEROCYCLE COMPOUNDS HAVING HIV INTEGRASE INHIBITING ACTIVITIES | SHIONOGI & CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| EP-0549601-A1 | METHOD OF PREPARING EXTENSIVELY FLUORINATED ALKYL BROMIDES. | RIEDEL DE HAEN AG (DE) | 1993-07-07 | — | — | EP | disclosed |
| US-4446075-A | DIRECT BROMINATION | RIEDEL-DE HAEN AG (DE) | 1984-05-01 | — | — | US | disclosed |
| EP-0034741-B1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED BROMOFLUOROBENZENE AND 3-BROMO-4-FLUOROBENZONITRILE | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1983-12-21 | — | — | EP | disclosed |
| EP-0034741-A2 | Process for the preparation of a substituted bromofluorobenzene and 3-bromo-4-fluorobenzonitrile | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1981-09-02 | — | — | EP | disclosed |