SCHEMBL688186

SCHEMBL688186

O=C(Br)c1ccc(C(=O)Br)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
CES2 O00748 7/20 0.45
CES1 P23141 7/20 0.45
OGG1 O15527 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
LMNA P02545 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
SRD5A2 P31213 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
PLK1 P53350 1/20 0.39
HDAC3 O15379 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769554 0.90 RAB9A (0.46) TP53TSHRLMNASRD5A2MAPT
SCHEMBL9173480 0.90 SRD5A2 (0.55) LMNAESR1ESR2SRD5A2MAPT
SCHEMBL10391056 0.87 TSHR (0.71) TP53TSHRCES2CES1CA1
SCHEMBL1991482 0.87 CES2 (0.65) CES2CES1OGG1CA1CA2
SCHEMBL7153626 0.87 MAPT (0.60) CES2CA1CA2LMNAESR1
SCHEMBL1563535 0.85 CES2 (0.62) CES2CES1CA1CA2KMT2A
SCHEMBL26253881 0.85 KMT2A (0.61) LMNAMAPTHPGDALDH1A1GAA
SCHEMBL1991237 0.85 TPMT (0.59) TP53TSHRCA1CA2
SCHEMBL1996245 0.85 CES2 (0.62) TSHRCES2CES1CA1CA2
SCHEMBL1290706 0.85 KMT2A (0.61) TP53TSHRCES2CES1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025229586-A1 POLYAMIDE GREASE THICKENING AGENT INV NYLON CHEMICALS AMERICAS, LLC (US) 2025-11-06 WO claimed
WO-2025120506-A1 PROCESS OF MAKING A POLYAMIDE GREASE THICKENING AGENT INV NYLON CHEMICALS AMERICAS, LLC (US) 2025-06-12 WO claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
US-20230265585-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF AQUAPORIN A/S (DK) 2023-08-24 US claimed
EP-4171787-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF Aquaporin A/S (DK) 2023-05-03 EP claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN claimed
CN-115867374-A Hollow fiber and method for producing same 水通道蛋白有限公司 2023-03-28 CN claimed
EP-3512905-B1 METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) BASF SE (DE) 2022-08-24 EP claimed
CN-109790292-B Process for preparing polybenzazole polymer (P) 巴斯夫欧洲公司 2022-05-31 CN claimed
WO-2022002788-A1 A HOLLOW FIBER AND A PROCESS FOR PREPARATION THEREOF AQUAPORIN A/S (DK) 2022-01-06 WO claimed
US-20200048418-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2020-02-13 US claimed
EP-3601408-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) Virginia Tech Intellectual Properties, Inc. (US) 2020-02-05 EP claimed
WO-2018183280-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY (US) 2018-10-04 WO claimed
EP-3381965-A1 A PROCESS FOR PREPARING A POLYARYLENESULFONE/POLYESTER BLOCK COPOLYMER (P) BASF SE (DE) 2018-10-03 EP claimed
US-9346023-B2 Flux enhancing agent for improving composite polyamide reverse osmosis membrane performance GENERAL ELECTRIC COMPANY (US) 2016-05-24 US claimed
EP-2888030-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE!OSMOSIS MEMBRANE PERFORMANCE General Electric Company (US) 2015-07-01 EP claimed
WO-2014031271-A1 AMINO-SILOXANE FLUX ENHANCING AGENT FOR IMPROVING COMPOSITE POLYAMIDE REVERSE|OSMOSIS MEMBRANE PERFORMANCE GENERAL ELECTRIC COMPANY (US) 2014-02-27 WO claimed
US-20140054228-A1 Novel Flux Enhancing Agent for Improving Composite Polyamide Reverse Osmosis Membrane Performance GENERAL ELECTRIC COMPANY (US) 2014-02-27 US claimed
US-4123420-A Aromatic copolyester composition containing phosphorus compounds UNITIKA LTD. (JP) 1978-10-31 US claimed
US-4011203-A FIBERS, FILMS TOYOBO CO., LTD. (JA) 1977-03-08 US claimed