SCHEMBL9769579

SCHEMBL9769579

O=C(Cl)c1ccc(Oc2cccc(Oc3ccc(C(=O)Cl)cc3)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 3/20 0.58
PARP15 Q460N3 2/20 0.58
PARP14 Q460N5 2/20 0.58
TNKS O95271 1/20 0.58
TNKS2 Q9H2K2 1/20 0.58
PARP2 Q9UGN5 1/20 0.58
FURIN P09958 2/20 0.56
F2 P00734 1/20 0.56
F10 P00742 1/20 0.56
AKR1C3 P42330 1/20 0.53
ALDH1A1 P00352 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
MITF O75030 1/20 0.50
GAA P10253 1/20 0.50
GFER P55789 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NLRP1 Q9C000 1/20 0.50
NOD2 Q9HC29 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7742691 0.92 PARP10 (0.64) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL727287 0.92 PARP10 (0.64) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL19612714 0.89 NAAA (0.56) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL9249310 0.88 PARP10 (0.64) PARP10PARP15PARP14AKR1C3ALDH1A1
SCHEMBL21786 0.88 PARP10 (0.64) PARP10PARP15PARP14AKR1C3ALDH1A1
SCHEMBL272345 0.87 PARP10 (0.58) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL9786679 0.87 PARP10 (0.58) PARP10PARP15PARP14TNKSTNKS2
Hydrochloric Acid SCHEMBL11161440 0.86 MAOB (0.58) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL10933601 0.86 AKR1C3 (0.60) PARP10PARP15PARP14TNKSTNKS2
SCHEMBL10496906 0.85 TNKS (0.60) PARP10PARP15PARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992526-A Preparation of polyarylate polymers of hydroxyaryl-substituted 1,6-diaza [4.] spirodilactams SHELL OIL COMPANY (US) 1991-02-12 US disclosed
US-4977235-A From aromatic dicarboxylic acids and hydroxyaryl-substituted 1,6-diaza(4.4)spirodilactams; molding materials; high glass transition temperatures SHELL OIL COMPANY (US) 1990-12-11 US disclosed
US-4968768-A Polyestercarbonate polymer containing spirodi lactam moiety SHELL OIL COMPANY (US) 1990-11-06 US disclosed
US-4910285-A Polyarylate polymers SHELL OIL COMPANY (US) 1990-03-20 US disclosed
WO-1985004178-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS SRI INTERNATIONAL (US) 1985-09-26 WO disclosed
EP-0119271-A4 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1985-07-01 EP disclosed
EP-0119271-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS. STANFORD RES INST INT (US) 1984-09-26 EP disclosed
EP-0119192-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS SRI INTERNATIONAL (US) 1984-09-26 EP disclosed
EP-0119202-A1 LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS SRI INTERNATIONAL (US) 1984-09-26 EP disclosed
WO-1984001161-A1 LIQUID CRYSTALLINE POLY(2,6-BENZOTHIAZOLE) COMPOSITIONS, PROCESS AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO disclosed
WO-1984001160-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO disclosed
WO-1984001162-A1 LIQUID CRYSTALLINE POLYMER COMPOSITIONS, PROCESS, AND PRODUCTS STANFORD RES INST INT (US) 1984-03-29 WO disclosed