Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769700 | 0.88 | LMNA (0.56) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9769708 | 0.87 | LMNA (0.52) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6932969 | 0.80 | ALDH1A1 (0.55) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9877535 | 0.75 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9864397 | 0.70 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9864700 | 0.70 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9769756 | 0.69 | TSHR (0.48) | LMNAMEN1KMT2AHCAR3 | |
| SCHEMBL9769718 | 0.68 | KMT2A (0.43) | LMNAMEN1KMT2AHCAR3 | |
| SCHEMBL9823387 | 0.67 | ALDH1A1 (0.49) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27182276 | 0.65 | LMNA (0.57) | LMNAPOLBMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071994-A | Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |