Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769708 | 0.90 | LMNA (0.52) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9769698 | 0.88 | LMNA (0.50) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6932969 | 0.83 | ALDH1A1 (0.55) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9769756 | 0.80 | TSHR (0.48) | LMNAMEN1KMT2AHCAR3 | |
| SCHEMBL9877535 | 0.78 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9864397 | 0.73 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9864700 | 0.73 | ALDH1A1 (0.48) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9823387 | 0.69 | ALDH1A1 (0.49) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9769718 | 0.69 | KMT2A (0.43) | LMNAMEN1KMT2AHCAR3 | |
| SCHEMBL9877541 | 0.68 | ALDH1A1 (0.38) | LMNAPOLBALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071994-A | Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |