Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769684 | 0.90 | HTT (0.47) | VCAM1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9320068 | 0.84 | LMNA (0.42) | VCAM1LMNAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL10470481 | 0.82 | HTT (0.35) | VCAM1LMNAMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9769695 | 0.80 | VCAM1 (0.51) | VCAM1LMNAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13871665 | 0.80 | VCAM1 (0.47) | VCAM1LMNAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL9769718 | 0.79 | KMT2A (0.43) | LMNAKMT2AMEN1 | |
| SCHEMBL10468618 | 0.78 | VCAM1 (0.56) | VCAM1LMNAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL6932969 | 0.73 | ALDH1A1 (0.55) | LMNASMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL5471880 | 0.68 | VCAM1 (1.00) | VCAM1LMNAMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10469420 | 0.68 | VCAM1 (0.34) | VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071994-A | Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |