Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13739852 | 0.83 | CES2 (0.52) | CES2CES1GAACYP2C19DAO | |
| SCHEMBL7512791 | 0.82 | DAO (0.57) | CES2CES1GAADAORAB9A | |
| SCHEMBL7515206 | 0.82 | DAO (0.57) | CES2CES1GAADAORAB9A | |
| SCHEMBL7512784 | 0.82 | DAO (0.57) | CES2CES1GAADAORAB9A | |
| SCHEMBL11523637 | 0.81 | CES2 (0.52) | CES2CES1GAADAORAB9A | |
| SCHEMBL11523638 | 0.81 | CES2 (0.52) | CES2CES1GAADAORAB9A | |
| SCHEMBL10332718 | 0.79 | RAB9A (0.49) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL10423692 | 0.79 | RAB9A (0.49) | CES2CES1DAORAB9ANPC1 | |
| SCHEMBL2509540 | 0.77 | HPGDS (0.58) | CES2CES1GAACYP2C19DAO | |
| SCHEMBL2474971 | 0.77 | HPGDS (0.58) | CES2CES1GAACYP2C19DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015659-A | Cognition activators to slow aging of the brain | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4987134-A | DISORDERS OF BRAIN FUNCTIONS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |
| US-4956358-A | ANTIBIOTICS, BACTERICIDES, CEPHALOSPORINS AND ISOCEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| US-4906659-A | Antibiotic tan-749, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| US-4897489-A | 2-/5-OXO-2-TETRAHYDROFURANY4-3-OXOISOXOL-IDINE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-30 | — | — | US | disclosed |
| US-4891427-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-01-02 | — | — | US | disclosed |
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0253337-A2 | Tricyclic cepham compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |
| EP-0249909-A1 | Tricyclic penam compounds, their production and their use | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0250096-A1 | Isoxazolone derivatives and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| EP-0191989-A1 | Antibiotic isoxazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1986-08-27 | — | — | EP | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |