SCHEMBL9769976

SCHEMBL9769976

CCN(O)C(=O)Oc1ccc(Cc2ccc(OC(=O)N(O)CC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 1/20 0.56
ELANE P08246 1/20 0.51
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
UBA2 Q9UBT2 1/20 0.40
LMNA P02545 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 1/20 0.38
LTA4H P09960 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
SRD5A2 P31213 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11065585 0.84 KMT2A (0.58) KMT2AMEN1RAB9ASMN1; SMN2HSD17B10
SCHEMBL10392581 0.81 KMT2A (0.55) KMT2AMEN1ELANERAB9ASMN1; SMN2
SCHEMBL8945465 0.78 MEN1 (0.71) KMT2AMEN1ELANERAB9ASMN1; SMN2
SCHEMBL723132 0.74 RAB9A (0.66) KMT2AELANERAB9ALMNALTA4H
SCHEMBL777803 0.72 ELANE (0.62) KMT2AMEN1ELANERAB9ASMN1; SMN2
SCHEMBL9302685 0.72 MEN1 (1.00) KMT2AMEN1RAB9ASMN1; SMN2HSD17B10
SCHEMBL13774087 0.70 RAB9A (0.73) KMT2AMEN1RAB9ALMNAALDH1A1
SCHEMBL6459728 0.70 PPARG (0.47) KMT2AELANELMNAL3MBTL1LTA4H
SCHEMBL5649619 0.70 RAB9A (0.66) KMT2AMEN1RAB9ASMN1; SMN2LMNA
SCHEMBL2907705 0.70 ELANE (0.59) KMT2AELANERAB9ASAE1UBA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5069992-A POLYURETHANE CONTAINING CARBOXYL GROUPS FUJI PHOTO FILM CO., LTD. (JP) 1991-12-03 US disclosed