Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769976 | 0.84 | KMT2A (0.56) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8945322 | 0.83 | KMT2A (0.85) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10392581 | 0.83 | KMT2A (0.55) | KMT2AMEN1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL16724735 | 0.81 | MEN1 (0.58) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL30439608 | 0.77 | LMNA (0.55) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| P-Tolyl Dimethylcarbamate SCHEMBL360147 | 0.76 | RAB9A (0.83) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11783210 | 0.75 | LMNA (0.57) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9302685 | 0.74 | MEN1 (1.00) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL2253704 | 0.73 | LMNA (0.55) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL18602051 | 0.73 | RAB9A (0.57) | KMT2AMEN1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446300-A | DIELECTRICS, FORMING TRIS/2-HYDROXYETHYL/ISOCYANURATE IN SITU FROM CYANURIC ACID AND ETHYLENE CARBONATE | THE P. D. GEORGE COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4113706-A | Aromatic imino acids and resins derived therefrom | THE P. D. GEORGE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4069209-A | DIELECTRIC COATINGS FOR WIRES | THE P. D. GEORGE COMPANY (US) | 1978-01-17 | — | — | US | disclosed |