SCHEMBL9770355

SCHEMBL9770355

Cc1ccccc1SCCSc1ccccc1C

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.48
MCHR1 Q99705 1/20 0.48
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MAPT P10636 2/20 0.47
TSHR P16473 2/20 0.45
ACHE P22303 2/20 0.45
NPC1 O15118 1/20 0.45
MAPK1 P28482 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.40
NOTUM Q6P988 1/20 0.39
HAO1 Q9UJM8 1/20 0.38
HSD17B10 Q99714 1/20 0.36
PTGS2 P35354 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29738631 1.00 HTR7 (0.48) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL5170853 0.90 HTR7 (0.46) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL10144088 0.88 PTGS2 (0.49) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL9116704 0.86 HTR7 (0.43) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL7410828 0.86 HTR7 (0.47) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL23132327 0.86 RAB9A (0.46) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL9315790 0.86 HTR7 (0.43) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL4186638 0.86 RAB9A (0.44) HTR7MCHR1RAB9ASMN1; SMN2MAPT
Bromide SCHEMBL11705861 0.84 HTR7 (0.46) HTR7MCHR1RAB9ASMN1; SMN2MAPT
SCHEMBL7264640 0.84 PTGS2 (0.53) HTR7MCHR1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
EP-0222343-B1 RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4792542-A CONTAINING AN AROMATIC SULFIDE FUJI PHOTO FILM CO., LTD. (JP) 1988-12-20 US disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed