Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770526 | 0.84 | BACE1 (0.52) | BACE1PPARDKDM4E | |
| SCHEMBL9770402 | 0.83 | BACE1 (0.58) | BACE1MAPK1TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL9770438 | 0.83 | TSHR (0.59) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770403 | 0.82 | BACE1 (0.58) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770536 | 0.81 | BACE1 (0.62) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770232 | 0.80 | BACE1 (0.64) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770148 | 0.78 | BACE1 (0.58) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770455 | 0.78 | BACE1 (0.58) | BACE1MAPK1TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL9480490 | 0.77 | BACE1 (0.80) | BACE1MAPK1TSHRHIF1AKDM4E | |
| SCHEMBL9770389 | 0.77 | BACE1 (0.64) | BACE1GAAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |