Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770438 | 0.86 | TSHR (0.59) | BACE1HIF1ATSHRMAPK1MAPT | |
| SCHEMBL9770536 | 0.84 | BACE1 (0.62) | BACE1HIF1ATSHRMAPK1NPC1 | |
| SCHEMBL9770402 | 0.84 | BACE1 (0.58) | BACE1HIF1ATSHRMAPK1MEN1 | |
| SCHEMBL9770232 | 0.82 | BACE1 (0.64) | BACE1HIF1ALTA4HTSHRMAPK1 | |
| SCHEMBL9770407 | 0.82 | BACE1 (0.52) | BACE1HIF1ATSHRMAPK1GAA | |
| SCHEMBL9770570 | 0.81 | BACE1 (0.76) | BACE1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL9770148 | 0.81 | BACE1 (0.58) | BACE1HIF1ATSHRMAPK1ALDH1A1 | |
| SCHEMBL9770455 | 0.81 | BACE1 (0.58) | BACE1HIF1ATSHRMAPK1NPC1 | |
| SCHEMBL9770444 | 0.80 | BACE1 (0.64) | BACE1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL9770412 | 0.80 | BACE1 (0.67) | BACE1LTA4HNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |