SCHEMBL9770428

SCHEMBL9770428

O=C(OCc1ccccc1-c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.61
ALDH1A1 P00352 3/20 0.59
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
ESR1 P03372 4/20 0.53
ESR2 Q92731 3/20 0.53
MAPT P10636 2/20 0.52
RAB9A P51151 2/20 0.52
PPARG P37231 1/20 0.51
SLC6A2 P23975 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
SLC6A3 Q01959 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4070163 0.85 LMNA (0.70) LMNAALDH1A1KMT2AMEN1ESR1
SCHEMBL4577944 0.83 PPARG (0.65) LMNAALDH1A1KMT2AMAPTRAB9A
SCHEMBL7618738 0.80 KMT2A (0.55) KMT2AFFAR1FFAR4
SCHEMBL7618735 0.80 KMT2A (0.55) KMT2AFFAR1FFAR4
SCHEMBL9770191 0.79 ESR1 (0.62) LMNAALDH1A1KMT2AMEN1ESR1
SCHEMBL831262 0.78 MAPT (0.68) LMNAALDH1A1KMT2AMEN1ESR1
SCHEMBL3628980 0.78 ESR1 (0.61) LMNAALDH1A1KMT2AMEN1ESR1
SCHEMBL5085480 0.77 PPARG (0.71) LMNAALDH1A1KMT2AMAPTRAB9A
SCHEMBL6393257 0.77 LMNA (0.58) LMNAALDH1A1KMT2AMEN1ESR1
SCHEMBL6394260 0.77 ESR1 (0.56) LMNAALDH1A1KMT2AMEN1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed