SCHEMBL831262

SCHEMBL831262

O=C(OCc1ccccc1Cl)c1ccc(O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.68
RAB9A P51151 3/20 0.68
NPC1 O15118 2/20 0.64
L3MBTL1 Q9Y468 2/20 0.60
LMNA P02545 1/20 0.60
THRB P10828 1/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
CASP3 P42574 2/20 0.55
SENP8 Q96LD8 2/20 0.55
SENP7 Q9BQF6 2/20 0.55
SENP6 Q9GZR1 2/20 0.55
MMP1 P03956 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP12 P39900 1/20 0.55
NR4A2 P43354 1/20 0.53
TP53 P04637 1/20 0.52
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14129928 0.95 MAPT (0.63) MAPTRAB9ANPC1L3MBTL1LMNA
SCHEMBL5421974 0.90 L3MBTL1 (0.72) MAPTRAB9ANPC1L3MBTL1THRB
SCHEMBL7542989 0.89 NR4A2 (0.68) MAPTRAB9ANPC1L3MBTL1LMNA
SCHEMBL4070163 0.88 LMNA (0.70) MAPTRAB9ANPC1LMNAMEN1
SCHEMBL7536304 0.84 MAPT (0.61) MAPTRAB9ANPC1L3MBTL1LMNA
SCHEMBL9750057 0.84 RAB9A (0.58) MAPTRAB9ANPC1L3MBTL1THRB
SCHEMBL9750015 0.83 TYR (0.58) MAPTRAB9ANPC1L3MBTL1CASP3
SCHEMBL11111310 0.82 LMNA (0.58) MAPTRAB9ANPC1L3MBTL1LMNA
SCHEMBL27455851 0.81 RAB9A (0.65) MAPTRAB9ANPC1L3MBTL1LMNA
SCHEMBL9770191 0.81 ESR1 (0.62) MAPTRAB9ANPC1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4638340-A PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR RICOH COMPANY, LTD. (JP) 1987-01-20 US claimed
US-4636819-A SUPPORT, LEUCO DYE, DEVELOPER, WATER SOLUBLE RESIN RICOH COMPANY, LTD. (JP) 1987-01-13 US claimed
EP-4022391-B1 HEAT SENSITIVE RECORDING MATERIAL WITH NON-PHENOLIC COLOR DEVELOPERS SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2026-03-04 EP disclosed
EP-3636446-B1 RECORDING MATERIAL, RECORDING SHEET AND USE OF A COMPOUND AS COLOUR-DEVELOPING AGENT NIPPON SODA CO (JP) 2025-04-16 EP disclosed
CN-114667279-B Thermosensitive recording material containing non-phenolic color developer 索理思科技开曼公司 2025-03-25 CN disclosed
US-12151497-B2 Heat sensitive recording material with non-phenolic color developers SOLENIS TECHNOLOGIES, L.P. (US) 2024-11-26 US disclosed
US-12030328-B2 Thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2024-07-09 US disclosed
CN-115107391-B Thermosensitive recording medium, laser printing method and laser printing apparatus 株式会社理光 2024-04-19 CN disclosed
EP-4297978-A1 COMPOSITIONS AND METHODS FOR SENSITIZING HEAT MEDIA Solenis Technologies Cayman, L.P. (CH) 2024-01-03 EP disclosed
CN-117098671-A Compositions and methods for sensitizing thermal media 索理思科技开曼公司 2023-11-21 CN disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4642357-A FLUORAN DERIVATIVES SHIN NISSO KAKO CP., LTD. (JP) 1987-02-10 US disclosed
US-4638340-A PROTECTIVE AND DECOLORING INTERMEDIATE LAYERS TO PRODUCE SEPARATE AND DISTINCT COLOR RICOH COMPANY, LTD. (JP) 1987-01-20 US disclosed
US-4636819-A SUPPORT, LEUCO DYE, DEVELOPER, WATER SOLUBLE RESIN RICOH COMPANY, LTD. (JP) 1987-01-13 US disclosed
EP-0105376-B1 COLOR-DEVELOPING SHEET FOR USE IN NO-CARBON RECORDING SYSTEM MITSUBISHI PAPER MILLS, LTD. (JP) 1986-12-10 EP disclosed
US-4620204-A MILTILAYER-SUPPORT, HIGH TEMPERATURE THERMOSENSITIVE LAYER, VINYLIDENE CHLORIDE INTERMEDIATE LAYER AND LOW TEMPERATURE COLOR FORMING LAYER RICOH COMPANY, LTD. (JP) 1986-10-28 US disclosed
US-4613879-A 3-N-ISOBUTYLETHYLAMINO-6-METHYL-7-PHENYLAMINOFLUORAN SHIN NISSO KAKO CO., LTD. (JP) 1986-09-23 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
US-4590498-A HEAT AND PRESSURE SENESITIVE ELEMENTS; HIGH SPEED; FLORAN DYES; INTENSITY SHIN NISSO KAKO CO., LTD. (JP) 1986-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 MAPT 3842/4885RAB9A 2099/4885NPC1 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.