Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.70 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770370 | 0.87 | BACE1 (0.53) | BACE1ABCB1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9480490 | 0.87 | BACE1 (0.80) | BACE1MAPK1CYP2D6CYP2C19LMNA | |
| SCHEMBL9770570 | 0.85 | BACE1 (0.76) | BACE1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL9770393 | 0.85 | MAPT (0.64) | BACE1ABCB1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9770321 | 0.84 | BACE1 (0.76) | BACE1MAPK1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9770465 | 0.84 | BACE1 (0.76) | BACE1SMN1; SMN2CYP2D6CYP2C19LMNA | |
| SCHEMBL9770399 | 0.82 | BACE1 (0.62) | BACE1SMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL18543110 | 0.81 | ABCB1 (0.71) | ABCB1MAPK1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL9770430 | 0.81 | BACE1 (0.57) | BACE1MAPK1SMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL9770149 | 0.79 | BACE1 (0.67) | BACE1MAPK1ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |