Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.76 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480490 | 0.91 | BACE1 (0.80) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770570 | 0.90 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770465 | 0.89 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770389 | 0.88 | BACE1 (0.64) | BACE1KMT2AHSD17B10GAA | |
| SCHEMBL9770535 | 0.85 | BACE1 (0.57) | BACE1PKMKMT2AKDM1AMAOA | |
| SCHEMBL9770440 | 0.84 | BACE1 (0.70) | BACE1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9770149 | 0.83 | BACE1 (0.67) | BACE1KMT2AMEN1ALDH1A1PTGS1 | |
| SCHEMBL9770401 | 0.83 | BACE1 (0.67) | BACE1NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9770412 | 0.83 | BACE1 (0.67) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770562 | 0.83 | BACE1 (0.67) | BACE1KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |