Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.76 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9480490 | 0.94 | BACE1 (0.80) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770232 | 0.91 | BACE1 (0.64) | BACE1LTA4HKMT2AHSD17B10NR1H2 | |
| SCHEMBL9770570 | 0.90 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770321 | 0.89 | BACE1 (0.76) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770440 | 0.84 | BACE1 (0.70) | BACE1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL3131341 | 0.84 | BACE1 (0.64) | BACE1KMT2AHSD17B10NPC1RAB9A | |
| SCHEMBL9770149 | 0.83 | BACE1 (0.67) | BACE1LTA4HKMT2ASLC6A2PTGS1 | |
| SCHEMBL9770401 | 0.83 | BACE1 (0.67) | BACE1NPC1RAB9ASLC6A2PTGS1 | |
| SCHEMBL9770562 | 0.83 | BACE1 (0.67) | BACE1KMT2ANPC1RAB9ASLC6A2 | |
| SCHEMBL9770369 | 0.83 | BACE1 (0.67) | BACE1KMT2AHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |