Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | YWHAB | P31946 | 1/20 | 0.63 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265091 | 0.91 | HPGD (0.81) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL17117490 | 0.90 | KMT2A (0.67) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL11470220 | 0.90 | PTPN1 (0.73) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL17117372 | 0.89 | HPGD (0.65) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL20816070 | 0.88 | KDM4E (0.76) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL4361785 | 0.85 | ADAMTS5 (0.67) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL4737461 | 0.85 | MEN1 (0.78) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL8184182 | 0.84 | RECQL (0.70) | PTPN1HPGDKMT2AGAANPC1 | |
| SCHEMBL28650889 | 0.83 | PTPN1 (0.61) | PTPN1HPGDABCB1ABCG2KMT2A | |
| SCHEMBL5272168 | 0.83 | KMT2A (1.00) | HPGDKMT2APOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355593-A1 | N-methyl-D-aspartic Acid Receptor Modulators | UNIV EMORY (US) | 2023-11-09 | — | — | US | disclosed |
| US-11738008-B2 | N-methyl-D-aspartic acid receptor modulators | EMORY UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | AEGERA THERAPEUTICS, INC. (CA) | 2010-11-18 | — | — | US | disclosed |
| US-4981836-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292269-A1 | BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC3, BIRC2 | PTPN1 2195/4885HPGD 4038/4885ABCB1 269/4885 |
| US-20230355593-A1 | N-methyl-D-aspartic Acid Receptor Modulators | GRIN1, GRIN2A, GRM1 | PTPN1 2252/4885HPGD 1784/4885ABCB1 3518/4885 |
| US-11738008-B2 | N-methyl-D-aspartic acid receptor modulators | GRIN1, GRIN2A, GRM1 | PTPN1 2242/4885HPGD 1775/4885ABCB1 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.