Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670412 | 0.92 | L3MBTL1 (0.61) | PTPN1HPGDADAMTS5ALDH1A1GAA | |
| SCHEMBL28668952 | 0.86 | KMT2A (0.68) | HPGDADAMTS5ALDH1A1GAAMEN1 | |
| SCHEMBL4737461 | 0.84 | MEN1 (0.78) | PTPN1ABCB1HPGDABCG2ALDH1A1 | |
| SCHEMBL28676238 | 0.84 | GRIN1 (0.53) | PTPN1HPGDADAMTS5ALDH1A1GAA | |
| SCHEMBL9770486 | 0.83 | PTPN1 (0.78) | PTPN1ABCB1HPGDABCG2ADAMTS5 | |
| SCHEMBL28654035 | 0.82 | ALDH1A1 (0.77) | HPGDADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL28655075 | 0.81 | ALDH1A1 (0.59) | HPGDADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL9265091 | 0.81 | HPGD (0.81) | PTPN1ABCB1HPGDABCG2ADAMTS5 | |
| SCHEMBL28668119 | 0.81 | ALDH1A1 (0.59) | HPGDADAMTS5ALDH1A1MEN1KMT2A | |
| SCHEMBL25811671 | 0.81 | ALDH1A1 (0.63) | HPGDALDH1A1MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |