Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL11245662 | 0.92 | RXRA (0.38) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL8649981 | 0.89 | CYP3A4 (0.40) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL11228612 | 0.86 | RXRA (0.35) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL31085264 | 0.85 | RXRA (0.41) | RXRARXRBCYP3A4KARS1CCNE1 | |
| SCHEMBL9770709 | 0.82 | ALDH1A1 (0.40) | HPGDHSD17B10RXRARXRBCYP3A4 | |
| SCHEMBL12074862 | 0.81 | KARS1 (0.43) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL6554250 | 0.81 | RXRA (0.38) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL29743366 | 0.81 | RXRA (0.38) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL3175854 | 0.80 | RXRA (0.57) | HPGDGFERHSD17B10RXRARXRB | |
| SCHEMBL24780985 | 0.79 | PDK2 (0.41) | HPGDGFERHSD17B10RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332970-A | Acetyl hydrindacenes, acetyl indanes, mixtures of same, processes for preparing same and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-06-01 | — | — | US | claimed |
| US-4289661-A | PREPARATION FROM CUMENE AND ISOPRENE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-09-15 | — | — | US | claimed |
| CN-1148400-C | polyimide and polyamic acid | 三井化学株式会社 | 2004-05-05 | — | — | CN | disclosed |
| CN-1366534-A | Polyimides and polyamide acids | MITSUI CHEMICALS INC (JP) | 2002-08-28 | — | — | CN | disclosed |
| US-4987261-A | Diaminoindane derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-01-22 | — | — | US | disclosed |
| US-4332970-A | Acetyl hydrindacenes, acetyl indanes, mixtures of same, processes for preparing same and organoleptic uses thereof | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-06-01 | — | — | US | disclosed |
| US-4305967-A | Flavoring with a mixture of acetyl hydrindacenes and acetyl indanes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4305411-A | FLAVORED SMOKING TOBACCO | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-12-15 | — | — | US | disclosed |
| US-4289661-A | PREPARATION FROM CUMENE AND ISOPRENE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4284819-A | FOOD FLAVORS, PERFUMES, TOBACCO FLAVORS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4260511-A | DETERGENTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4209543-A | Flavoring with a mixture of acetyl hydrindacenes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-06-24 | — | — | US | disclosed |