Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | SI | P14410 | 1/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770647 | 0.85 | RAB9A (0.66) | RAB9AKMT2ARPS6KA2NPC1RECQL | |
| SCHEMBL10050510 | 0.82 | RAB9A (0.85) | RAB9AKMT2ANPC1RECQLPOLB | |
| SCHEMBL18501643 | 0.81 | RAB9A (0.83) | RAB9AKMT2ANPC1RECQLPOLB | |
| SCHEMBL15922624 | 0.80 | RAB9A (0.81) | RAB9AKMT2ANPC1RECQLPOLB | |
| SCHEMBL8614129 | 0.79 | RAB9A (0.50) | RAB9AKMT2ARPS6KA2NPC1HSD17B10 | |
| SCHEMBL30296449 | 0.79 | CASP3 (0.88) | KMT2ACASP3GAAMEN1 | |
| SCHEMBL45154 | 0.79 | CASP3 (0.88) | KMT2ACASP3GAAMEN1 | |
| Hydrochloric Acid SCHEMBL8616864 | 0.78 | MGAM (0.49) | RAB9AKMT2ANPC1HSD17B10HPGD | |
| SCHEMBL9770478 | 0.78 | SCN2A (0.54) | RAB9ARPS6KA2NPC1POLBHPGD | |
| SCHEMBL10441170 | 0.77 | ALDH1A1 (0.50) | RAB9ARPS6KA2NPC1CASP3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001115-A | Prodrugs of biologically active hydroxyaromatic compounds | UNIVERSITY OF FLORIDA (US) | 1991-03-19 | — | — | US | disclosed |