Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770570 | 0.92 | BACE1 (0.76) | BACE1PTGS1SLC6A2PPARDADRB3 | |
| SCHEMBL9770149 | 0.88 | BACE1 (0.67) | BACE1PTGS1SLC6A2ADRB3ADRB2 | |
| SCHEMBL9770412 | 0.88 | BACE1 (0.67) | BACE1PTGS1SLC6A2PPARDADRB3 | |
| SCHEMBL10338981 | 0.87 | BACE1 (0.61) | BACE1USP2TSHRPPARDKDM4E | |
| SCHEMBL9770401 | 0.85 | BACE1 (0.67) | BACE1TSHRPTGS1SLC6A2PPARD | |
| SCHEMBL9770369 | 0.85 | BACE1 (0.67) | BACE1USP2TSHRPTGS1SLC6A2 | |
| SCHEMBL9480490 | 0.85 | BACE1 (0.80) | BACE1TSHRPTGS1SLC6A2ADRB3 | |
| SCHEMBL9770450 | 0.85 | BACE1 (0.63) | BACE1TSHRPTGS1SLC6A2PPARD | |
| SCHEMBL9770406 | 0.85 | BACE1 (0.60) | BACE1PTGS1SLC6A2PPARDADRB3 | |
| SCHEMBL9770402 | 0.83 | BACE1 (0.58) | BACE1TSHRADRB3ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |