Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770570 | 0.85 | BACE1 (0.76) | BACE1PPARDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL9770562 | 0.85 | BACE1 (0.67) | BACE1PPARDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL9770444 | 0.85 | BACE1 (0.64) | BACE1PPARDKMT2ASMN1; SMN2PTGS1 | |
| SCHEMBL9770402 | 0.83 | BACE1 (0.58) | BACE1KMT2ASMN1; SMN2MAPTADRB2 | |
| SCHEMBL9770149 | 0.82 | BACE1 (0.67) | BACE1KMT2AMAPTPTGS1SLC6A2 | |
| SCHEMBL9770412 | 0.82 | BACE1 (0.67) | BACE1PPARDKMT2ASMN1; SMN2MAPT | |
| SCHEMBL9770503 | 0.82 | BACE1 (0.57) | BACE1PPARDKMT2APTGS1SLC6A2 | |
| SCHEMBL9770439 | 0.81 | BACE1 (0.60) | BACE1PPARDKMT2ASMN1; SMN2PTGS1 | |
| SCHEMBL9770377 | 0.81 | BACE1 (0.67) | BACE1SMN1; SMN2HPGDPOLBRAB9A | |
| SCHEMBL9770536 | 0.81 | BACE1 (0.62) | BACE1KMT2ASMN1; SMN2ADRB3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |