Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537313 | 0.79 | GAA (0.52) | CYP1A2TDP1PKMSMN1; SMN2LMNA | |
| SCHEMBL9770730 | 0.73 | TDP1 (0.50) | CYP1A2TDP1PKMALOX15MAPK1 | |
| SCHEMBL10994685 | 0.69 | CYP1A2 (0.70) | CYP1A2TDP1PKMMAPK1SMN1; SMN2 | |
| SCHEMBL9535392 | 0.69 | CYP1A2 (0.55) | CYP1A2TDP1PKMALOX15MAPK1 | |
| SCHEMBL9534148 | 0.69 | CYP1A2 (0.55) | CYP1A2TDP1PKMALOX15MAPK1 | |
| SCHEMBL10696259 | 0.68 | CYP1A2 (0.43) | CYP1A2TDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL11465861 | 0.68 | MAPK1 (0.39) | CYP1A2TDP1PKMALOX15MAPK1 | |
| SCHEMBL9535677 | 0.68 | TDP1 (0.50) | CYP1A2TDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL9536991 | 0.68 | CYP1A2 (0.50) | CYP1A2TDP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL10997189 | 0.67 | CYP1A2 (0.66) | CYP1A2TDP1PKMALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |