Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536991 | 0.82 | CYP1A2 (0.50) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL9535677 | 0.82 | TDP1 (0.50) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL9770496 | 0.82 | CYP1A2 (0.43) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL10696259 | 0.82 | CYP1A2 (0.43) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL9534241 | 0.82 | PKM (0.50) | CYP1A2TDP1PKMSMN1; SMN2MAPT | |
| SCHEMBL28345207 | 0.80 | CHEK1 (0.51) | GAACYP1A2TDP1SMN1; SMN2MAPT | |
| SCHEMBL9770674 | 0.79 | CYP1A2 (0.50) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL9534426 | 0.79 | ALDH1A1 (0.43) | CYP1A2TDP1PKMMAPTHSD17B10 | |
| SCHEMBL9535141 | 0.77 | CYP1A2 (0.50) | GAACYP1A2TDP1PKMSMN1; SMN2 | |
| SCHEMBL10695623 | 0.77 | KDM4E (0.51) | SMN1; SMN2MAPTHPGDPARP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |