SCHEMBL9770701

SCHEMBL9770701

Cc1ccc(C)c2c1CCC2(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19870686 0.84 TP53 (0.41)
SCHEMBL19870678 0.84 HDAC4 (0.31)
SCHEMBL11883539 0.81 CES2 (0.30)
SCHEMBL9770695 0.74 ALDH1A1 (0.37) ALDH1A1
SCHEMBL9079561 0.72 TP53 (0.39) ALDH1A1
SCHEMBL18870470 0.71 KCNH2 (0.30)
SCHEMBL25027774 0.71 CD44 (0.38) ALDH1A1HTR2CHTR2B
SCHEMBL17019720 0.71 MAOA (0.31)
SCHEMBL17019672 0.71 MAOA (0.31)
SCHEMBL26607001 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4987261-A Diaminoindane derivatives MITSUI TOATSU CHEMICALS, INC. (JP) 1991-01-22 US disclosed
US-4572796-A 1,1,4,7-Tetramethyl-3-indanone, product produced thereby and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1986-02-25 US disclosed