Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770895 | 0.75 | SMN1; SMN2 (0.32) | SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL9770869 | 0.71 | HDAC3 (0.38) | SMN1; SMN2RAB9APOLBALDH1A1MEN1 | |
| SCHEMBL9770947 | 0.60 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ANPC1TP53POLB | |
| SCHEMBL9824605 | 0.59 | MAPT (0.31) | SMN1; SMN2NPC1ALDH1A1MEN1MAPT | |
| SCHEMBL7354463 | 0.57 | PDE4D (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL14945842 | 0.56 | ALDH1A1 (0.40) | SMN1; SMN2RAB9ANPC1TP53POLB | |
| SCHEMBL13216223 | 0.56 | POLB (0.47) | SMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL3743731 | 0.55 | AKR1B1 (0.59) | SMN1; SMN2POLBHPGDALDH1A1MEN1 | |
| SCHEMBL13225709 | 0.55 | KMT2A (0.43) | SMN1; SMN2RAB9ANPC1TP53POLB | |
| SCHEMBL30591279 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |