Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824605 | 0.68 | MAPT (0.31) | SMN1; SMN2NPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL2437756 | 0.67 | ALDH1A1 (0.44) | NPC1RAB9AHPGDALDH1A1MAPT | |
| SCHEMBL3633337 | 0.65 | ADRA2A (0.43) | POLBHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL3743731 | 0.63 | AKR1B1 (0.59) | SMN1; SMN2POLBHPGDALDH1A1MAPT | |
| SCHEMBL8601531 | 0.63 | HTT (0.31) | — | |
| SCHEMBL23374527 | 0.62 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ATP53POLB | |
| SCHEMBL7354463 | 0.62 | PDE4D (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3019690 | 0.62 | ALDH1A1 (0.47) | SMN1; SMN2HPGDALDH1A1MAPTMEN1 | |
| SCHEMBL7041011 | 0.62 | OPRD1 (0.45) | SMN1; SMN2POLBHPGDALDH1A1MAPT | |
| SCHEMBL1408532 | 0.61 | ALDH1A1 (0.44) | SMN1; SMN2HPGDALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |