SCHEMBL9770895

SCHEMBL9770895

COC(=O)Cc1sc(F)c(NC(=S)N2CCCC=N2)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9770880 0.75 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1RAB9A
SCHEMBL9042780 0.75 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL9770873 0.69 KMT2A (0.33) SMN1; SMN2ALDH1A1RAB9A
SCHEMBL9043547 0.68
SCHEMBL9770869 0.67 HDAC3 (0.38) SMN1; SMN2ALDH1A1RAB9A
SCHEMBL9041811 0.66
SCHEMBL10523796 0.63
SCHEMBL9770917 0.63 ALDH1A1 (0.44) ALDH1A1
SCHEMBL8601531 0.60 HTT (0.31)
SCHEMBL9074226 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5039331-A Condensed heterocyclic derivatives and herbicides NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1991-08-13 US disclosed
EP-0304920-A2 Condensed heterocyclic derivatives, process for their production and herbicides NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-03-01 EP disclosed