Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PPIA | P62937 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318227 | 0.76 | MAPT (0.57) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL28451182 | 0.76 | ALDH1A1 (0.71) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL9770834 | 0.76 | MEN1 (0.55) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL27437593 | 0.75 | MAPT (0.56) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL9763219 | 0.74 | CTSD (0.70) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL11298067 | 0.73 | ALDH1A1 (0.72) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL8095620 | 0.72 | ALDH1A1 (0.70) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL6971514 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL296470 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTGAAKDM4EMEN1 | |
| SCHEMBL31621278 | 0.72 | ALDH1A1 (0.76) | ALDH1A1MAPTGAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987135-A | Leukemia, melanoma | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-22 | — | — | US | claimed |