Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770953 | 0.84 | HPGD (0.36) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9770873 | 0.79 | KMT2A (0.33) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9764390 | 0.78 | ALDH1A1 (0.44) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9770973 | 0.77 | PPOX (0.36) | MAPTHPGDALDH1A1KMT2AGAA | |
| SCHEMBL9770943 | 0.77 | CYP4F2 (0.41) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL25047377 | 0.75 | ALDH1A1 (0.57) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10992090 | 0.74 | KMT2A (0.45) | MAPTLMNAHPGDSMN1; SMN2KMT2A | |
| SCHEMBL27691074 | 0.74 | MAPT (0.49) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4681898 | 0.71 | MAPT (0.51) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL10919784 | 0.71 | CCR1 (0.43) | MAPTLMNAHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |