Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770931 | 0.84 | MAPT (0.43) | HPGDGAAWDR5SMN1; SMN2MAPT | |
| SCHEMBL9770963 | 0.77 | SLC6A3 (0.34) | HPGDPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9770913 | 0.75 | ALDH1A1 (0.34) | HPGDPOLBGAASMN1; SMN2MAPT | |
| SCHEMBL9770873 | 0.75 | KMT2A (0.33) | HPGDPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9770973 | 0.75 | PPOX (0.36) | HPGDPOLBGAARAB9AMAPT | |
| SCHEMBL9770999 | 0.72 | ALDH1A1 (0.31) | POLBLMNAALDH1A1 | |
| SCHEMBL10410242 | 0.67 | NPC1 (0.43) | HPGDPOLBGAAWDR5SMN1; SMN2 | |
| SCHEMBL9242888 | 0.67 | NPC1 (0.49) | HPGDPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9770926 | 0.66 | CYP19A1 (0.33) | — | |
| SCHEMBL9770905 | 0.64 | NAAA (0.39) | HPGDPOLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039331-A | Condensed heterocyclic derivatives and herbicides | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0304920-A2 | Condensed heterocyclic derivatives, process for their production and herbicides | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-03-01 | — | — | EP | disclosed |