Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771085 | 0.94 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9771230 | 0.89 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9866486 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9771035 | 0.78 | SLC6A3 (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12069271 | 0.77 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL15328470 | 0.76 | ALDH1A1 (0.78) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9866470 | 0.75 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL9771140 | 0.75 | EPHX2 (0.71) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL12069951 | 0.74 | MEN1 (0.89) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL22429105 | 0.74 | CCR6 (0.66) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302896-B1 | N-(W-SUBSTITUTED ALKYL)-N'-[(IMIDAZOLE-4-YL)ALKYL]GUANIDINE | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-08-14 | — | — | EP | disclosed |
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |
| US-5010095-A | Antiallergens, congestive heart failure | CEDONA PHARMACEUTICALS B.V. (NL) | 1991-04-23 | — | — | US | disclosed |