Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771085 | 0.87 | ALDH1A1 (0.58) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL9771127 | 0.84 | ALDH1A1 (0.57) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL9771230 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL15328470 | 0.79 | ALDH1A1 (0.78) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL9771140 | 0.78 | EPHX2 (0.71) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL28660632 | 0.78 | MTNR1A (0.58) | ALDH1A1KMT2AMAPT | |
| SCHEMBL14946919 | 0.76 | ALDH1A1 (0.69) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL26512476 | 0.76 | ALDH1A1 (0.69) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL15328268 | 0.76 | SMN1; SMN2 (0.77) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A | |
| SCHEMBL28982552 | 0.74 | ALDH1A1 (0.71) | ALDH1A1ALOX12SMN1; SMN2MITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021431-A | H-1 antagonist, h-2 agonist for treating hypertension, cardiac disease or arterial occlusion | HEUMANN PHARMA GMBH & CO. (DE) | 1991-06-04 | — | — | US | disclosed |