Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9771652 | 0.79 | GLA (0.36) | GLAMAPTADRB2ALDH1A1LMNA | |
| SCHEMBL10581409 | 0.76 | SLC2A1 (0.35) | GLAMAPTALDH1A1HPGDLMNA | |
| SCHEMBL8412603 | 0.70 | KMT2A (0.41) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2878100 | 0.70 | GRM8 (0.32) | GLAALDH1A1LMNA | |
| SCHEMBL9771631 | 0.69 | GLA (0.44) | GLAMAPTADRB2ALDH1A1ADRB1 | |
| SCHEMBL3666022 | 0.69 | GPR35 (0.43) | GLAALDH1A1MEN1KMT2A | |
| SCHEMBL8799644 | 0.68 | GLA (0.38) | GLAMAPTADRB2ALDH1A1MEN1 | |
| SCHEMBL6414085 | 0.68 | MAPT (0.42) | GLAMAPTADRB2ALDH1A1HPGD | |
| SCHEMBL10860894 | 0.68 | ALDH1A1 (0.39) | MAPTALDH1A1HPGDLMNAMEN1 | |
| SCHEMBL6001727 | 0.67 | MAPT (0.54) | GLAMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992586-A | Dehalogenation of a halonitrobenzene compound | L'OREAL (FR) | 1991-02-12 | — | — | US | disclosed |