Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 3/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797902 | 0.83 | ALDH1A1 (0.43) | MAPTALDH1A1PKMKMT2APOLB | |
| SCHEMBL8797956 | 0.76 | ADRB2 (0.32) | ALDH1A1ADRB2 | |
| SCHEMBL8798677 | 0.75 | ALDH1A1 (0.39) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9771631 | 0.71 | GLA (0.44) | GLAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL108993 | 0.71 | KMT2A (0.62) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL29516649 | 0.71 | KMT2A (0.62) | MAPTALDH1A1MEN1PKMKMT2A | |
| SCHEMBL7719478 | 0.69 | GLA (0.39) | GLAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6414085 | 0.69 | MAPT (0.42) | GLAMAPTALDH1A1MEN1PKM | |
| SCHEMBL9771663 | 0.68 | GLA (0.38) | GLAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9795841 | 0.68 | KMT2A (0.50) | MAPTALDH1A1MEN1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532039-B1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | BRISTOL MYERS SQUIBB CO (US) | 1997-12-03 | — | — | EP | disclosed |
| EP-0532039-A1 | N1-trifluoroalkyl substituted 2-nitro-p-phenylenediamine dyes | Bristol-Myers Squibb Company (US) | 1993-03-17 | — | — | EP | disclosed |