Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid Phenyl Ester SCHEMBL27286026 | 0.87 | ALDH1A1 (0.55) | LMNAELANEALDH1A1CYP3A4HSD17B10 | |
| Anisole SCHEMBL28263420 | 0.86 | LMNA (0.53) | LMNAELANEALDH1A1MAPTMEN1 | |
| Acetic Acid Phenyl Ester SCHEMBL1865089 | 0.85 | ELANE (0.56) | LMNAELANEALDH1A1MAPTHPGD | |
| Acetic Acid Phenyl Ester SCHEMBL7717862 | 0.85 | ALDH1A1 (0.61) | LMNAELANEALDH1A1MAPTTHRB | |
| Acetic Acid Propyl Ester SCHEMBL11290042 | 0.84 | THRB (0.54) | LMNAALDH1A1MAPTMEN1THRB | |
| Acetic Acid Phenyl Ester SCHEMBL8190438 | 0.83 | ELANE (0.58) | LMNAELANEALDH1A1MAPTMEN1 | |
| Acetic Acid Phenyl Ester SCHEMBL1870720 | 0.83 | ELANE (0.62) | LMNAELANEALDH1A1MAPTMEN1 | |
| Acetic Acid Phenyl Ester SCHEMBL35500 | 0.82 | ELANE (0.72) | LMNAELANEALDH1A1MAPTMEN1 | |
| Acetic Acid Propyl Ester SCHEMBL28263423 | 0.82 | ALDH1A1 (0.61) | LMNAALDH1A1HPGDGAATDP1 | |
| Acetic Acid Phenyl Ester SCHEMBL6422166 | 0.82 | ELANE (0.72) | LMNAELANEALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032523-A | Preparation of optically active esters | LION CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |