Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338040 | 0.79 | GAA (0.39) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL28815661 | 0.79 | GAA (0.39) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL12003317 | 0.77 | GLA (0.39) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL3260744 | 0.76 | HCAR2 (0.48) | GAAMGAMSIMGAM2L3MBTL1 | |
| SCHEMBL12393899 | 0.74 | NR1I2 (0.45) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL11601388 | 0.74 | GLA (0.41) | GAAMGAMSIMGAM2CYP1A2 | |
| SCHEMBL1147121 | 0.74 | — | — | |
| SCHEMBL2335067 | 0.73 | CYP2C9 (0.41) | GAAMGAMSIMGAM2CYP2C9 | |
| SCHEMBL87647 | 0.72 | — | — | |
| SCHEMBL1149476 | 0.71 | ALOX15 (0.42) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983328-A | ANTITUMOR AGENTS | BRISTOL-MYERS COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4518532-A | ANTITIMOR | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-05-21 | — | — | US | disclosed |