Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338040 | 0.80 | GAA (0.39) | GAAMGAMSIMGAM2RAB9A | |
| SCHEMBL28815661 | 0.80 | GAA (0.39) | GAAMGAMSIMGAM2RAB9A | |
| SCHEMBL12003317 | 0.78 | GLA (0.39) | GAAMGAMSIMGAM2RAB9A | |
| SCHEMBL19944332 | 0.78 | L3MBTL1 (0.32) | HCAR2GAAMGAMSIMGAM2 | |
| SCHEMBL11601388 | 0.76 | GLA (0.41) | GAAMGAMSIMGAM2RAB9A | |
| Acrylic Acid SCHEMBL30356562 | 0.76 | ALDH1A1 (0.43) | HCAR2GAAMGAMSIMGAM2 | |
| SCHEMBL10323476 | 0.76 | MEN1 (0.45) | GAAMEN1KMT2A | |
| SCHEMBL10323475 | 0.76 | MEN1 (0.45) | GAAMEN1KMT2A | |
| Acrylic Acid SCHEMBL2476698 | 0.76 | ALDH1A1 (0.43) | HCAR2GAAMGAMSIMGAM2 | |
| SCHEMBL9772247 | 0.76 | GAA (0.36) | GAAMGAMSIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906629-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2011-03-15 | — | — | US | disclosed |
| US-7649085-B2 | Saquinavir conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-01-19 | — | — | US | disclosed |
| EP-1809672-B1 | ATAZANAVIR CONJUGATES AND ANTIBIBODIES USEFUL IN IMMUNOSSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-09-09 | — | — | EP | disclosed |
| US-7569678-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-08-04 | — | — | US | disclosed |
| US-7482437-B2 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2008-01-24 | — | — | US | disclosed |
| EP-1809672-A1 | ATAZANAVIR CONJUGATES AND ANTIBIBODIES USEFUL IN IMMUNOSSAY | Roche Diagniostics GMBH (DE) | 2007-07-25 | — | — | EP | disclosed |
| US-20070155959-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2007-07-05 | — | — | US | disclosed |
| US-20070149565-A1 | Nelfinavir conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2007-06-28 | — | — | US | disclosed |
| US-20070148708-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SIGLER GERALD F | 2007-06-28 | — | — | US | disclosed |
| US-7157561-B2 | Methods of inhibiting transmission of a costimulatory signal of lymphocytes | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060264618-A1 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | DERAS INA | 2006-11-23 | — | — | US | disclosed |
| US-20060211107-A1 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | SIGLER GERALD F | 2006-09-21 | — | — | US | disclosed |
| WO-2006048300-A1 | ATAZANAVIR CONJUGATES AND ANTIBIBODIES USEFUL IN IMMUNOSSAY | ROCHE DIAGNIOSTICS GMBH (DE) | 2006-05-11 | — | — | WO | disclosed |
| EP-1519192-A2 | HIV Protease inhibitor conjugates and antibodies useful in ummunoassay | Roche Diagnostics GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| US-20050064517-A1 | Atazanavir conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2005-03-24 | — | — | US | disclosed |
| US-20040127689-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2004-07-01 | — | — | US | disclosed |
| EP-1409546-A2 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | Roche Diagnostics GmbH (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-20030100088-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2003-05-29 | — | — | US | disclosed |
| WO-2003006506-A2 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2003-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264618-A1 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | SERPINB1, DNPEP, SPINT2 | HCAR2 2622/4885GAA 251/4885MGAM 687/4885 |
| US-20030100088-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | HCAR2 1643/4885GAA 287/4885MGAM 1008/4885 |
| US-20050064517-A1 | Atazanavir conjugates and antibodies useful in immunoassay | DNPEP, DNTT, ADA | HCAR2 887/4885GAA 89/4885MGAM 1444/4885 |
| US-20040127689-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, DNPEP | HCAR2 1595/4885GAA 207/4885MGAM 1142/4885 |
| US-20060211107-A1 | PROTEASE INHIBITOR CONJUGATES AND ANTIBODIES USEFUL IN IMMUNOASSAY | SERPINB1, HPN, SPR | HCAR2 1004/4885GAA 394/4885MGAM 1104/4885 |
| US-20080021201-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | HCAR2 1013/4885GAA 394/4885MGAM 1103/4885 |
| US-20070148708-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SPR, HPN, SAMHD1 | HCAR2 826/4885GAA 367/4885MGAM 1358/4885 |
| US-20070155959-A1 | Protease inhibitor conjugates and antibodies useful in immunoassay | SERPINB1, HPN, SPR | HCAR2 1004/4885GAA 394/4885MGAM 1104/4885 |
| US-20070149565-A1 | Nelfinavir conjugates and antibodies useful in immunoassay | SAMHD1, SPR, CYP3A4 | HCAR2 673/4885GAA 682/4885MGAM 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.