Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | RXRB | P28702 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340618 | 0.96 | MAOB (0.67) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL11602002 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTGAAMAPT | |
| SCHEMBL978523 | 0.89 | MAOB (0.58) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL3232949 | 0.86 | SRD5A2 (0.90) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL50807 | 0.85 | KMT2A (0.73) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL402300 | 0.85 | SRD5A2 (0.87) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL977023 | 0.84 | MAOB (0.53) | SRD5A2SMN1; SMN2ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3002718 | 0.84 | MEN1 (0.53) | SRD5A2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL20830918 | 0.84 | KMT2A (0.67) | SMN1; SMN2ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11601531 | 0.84 | MAOB (0.69) | SMN1; SMN2ALDH1A1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | SRD5A2 1148/4885SMN1; SMN2 3930/4885ALDH1A1 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.