Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772371 | 0.90 | HPGD (0.38) | KDM4ENPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9772488 | 0.90 | HPGD (0.38) | KDM4ENPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9772460 | 0.86 | CYP11B1 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9772823 | 0.86 | HMOX1 (0.36) | KDM4ENPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL9772573 | 0.83 | HSD11B1 (0.38) | KDM4ENPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9772534 | 0.82 | RAB9A (0.41) | KDM4ENPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9772611 | 0.80 | SLC6A4 (0.34) | KDM4ENPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL15123750 | 0.79 | LCK (0.36) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL9772618 | 0.79 | POLB (0.46) | — | |
| SCHEMBL9772751 | 0.78 | HTR2A (0.44) | NPC1RAB9AL3MBTL1MAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041442-A | Antiulcer agents | SYNTEX (U.S.A.) INC. (US) | 1991-08-20 | — | — | US | disclosed |