Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25230809 | 0.89 | ALDH1A1 (0.43) | ALDH1A1RECQLNR1I2APPGAA | |
| SCHEMBL19342431 | 0.88 | ALDH1A1 (0.42) | ALDH1A1RECQLAPPGAAHRH3 | |
| SCHEMBL20969950 | 0.86 | PRSS1 (0.41) | ALDH1A1APPCA12CA1CA9 | |
| SCHEMBL6046899 | 0.86 | PRMT1 (0.43) | ALDH1A1RECQLAPPGAAHRH3 | |
| SCHEMBL6727999 | 0.86 | PRMT1 (0.43) | ALDH1A1RECQLAPPGAAHRH3 | |
| SCHEMBL28106819 | 0.83 | ALDH1A1 (0.75) | ALDH1A1RECQLNR1I2APPGAA | |
| SCHEMBL48239 | 0.83 | ALDH1A1 (0.75) | ALDH1A1RECQLNR1I2APPGAA | |
| SCHEMBL19995157 | 0.83 | APP (0.47) | ALDH1A1APPCA12CA1CA9 | |
| SCHEMBL38655982 | 0.82 | KCNA3 (0.48) | GAAHRH3 | |
| SCHEMBL12711671 | 0.82 | APP (0.65) | ALDH1A1RECQLNR1I2APPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0744391-B1 | Process for the preparation of aromatic acetyles using palladacyclen as acatalysts | AVENTIS RES & TECH GMBH & CO (DE) | 2001-09-26 | — | — | EP | claimed |
| CN-117751113-A | Aromatic acetylene derivative and preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023011573-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2023011573-A1 | AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-02-09 | — | — | WO | disclosed |
| WO-2020008826-A1 | COMPOUNDS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC株式会社 | 2020-01-09 | — | — | WO | disclosed |
| EP-3000833-B1 | MICELLES COMPRISING A TRIBLOCK COPOLYMER AND A THERAPEUTIC AGENT | INTEZYNE TECH INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-9944754-B2 | Block copolymers for stable micelles | INTEZYNE TECHNOLOGIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944752-B2 | Block copolymers for stable micelles | INTEZYNE TECHNOLOGIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170253699-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | INTEZYNE TECHNOLOGIES, INC. | 2017-09-07 | — | — | US | disclosed |
| US-20170240703-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | INTEZYNE TECHNOLOGIES, INC. | 2017-08-24 | — | — | US | disclosed |
| US-20060172914-A1 | Synthesis of hybrid block copolymers and uses thereof | INTEZYNE TECHNOLOGIES, INC. | 2006-08-03 | — | — | US | disclosed |
| WO-2006074202-A2 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060142506-A1 | Heterobifunctional poly(ethylene glycol) and uses thereof | INTEZYNE TECHNOLOGIES, INC. | 2006-06-29 | — | — | US | disclosed |
| WO-2006047419-A2 | HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2006-05-04 | — | — | WO | disclosed |
| WO-2005103031-A1 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005103002-A2 | NOVEL ALKYNE COMPOUNDS WITH AN MCH-ANTAGONISTIC ACTION AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| US-20050234101-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-6673267-B2 | EXHIBING HIGH REFRACTIVE INDEX ANISOTROPY; PHOTOSTABILITY; USEFUL IN PRODUCING COLORED FILMS, DISPLAYS, OPTICAL RECORDING MATERIALS, OPTICAL COMPENSATORS, POLARIZERS, REFLECTOR PLATES, AND SCATTERING PLATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-01-06 | — | — | US | disclosed |
| US-20020006479-A1 | Phenylacetylene compound, liquid crystal composition, polymer, optically anisotropic product, and liquid crystal or optical element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| US-5886240-A | Process for preparing aromatic acetylenes using palladacycles as catalysts | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142506-A1 | Heterobifunctional poly(ethylene glycol) and uses thereof | GNE, ALG1, EPHX2 | ALDH1A1 1837/4885RECQL 3871/4885NR1I2 4592/4885 |
| US-20170240703-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | ABCB4, CLTB, EPHA2 | ALDH1A1 4634/4885RECQL 2362/4885NR1I2 3510/4885 |
| US-20170253699-A1 | BLOCK COPOLYMERS FOR STABLE MICELLES | ABCB4, CLTB, EPHA2 | ALDH1A1 4634/4885RECQL 2362/4885NR1I2 3510/4885 |
| US-20050234101-A1 | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds | MCHR1, GPR119, MCHR2 | ALDH1A1 3567/4885RECQL 4769/4885NR1I2 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.