Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357342 | 0.87 | LMNA (0.34) | ESR1KMT2ANPSR1LMNACYP3A4 | |
| SCHEMBL97810 | 0.87 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL14066995 | 0.84 | MEN1 (0.36) | KMT2AMAPTGAAHSD17B10 | |
| SCHEMBL14725419 | 0.81 | ESR1 (0.36) | ESR1ESR2KMT2ANPSR1HSP90AA1 | |
| SCHEMBL26374252 | 0.80 | LMNA (0.33) | KMT2ALMNACYP3A4CYP2C19HSD17B10 | |
| SCHEMBL26374280 | 0.78 | MEN1 (0.33) | KMT2A | |
| SCHEMBL683427 | 0.78 | ALDH1A1 (0.34) | KMT2ALMNAHSD11B1 | |
| SCHEMBL26080956 | 0.77 | ESR1 (0.37) | ESR1ESR2MAPTLMNACYP1A2 | |
| SCHEMBL25504763 | 0.76 | ESR1 (0.33) | ESR1ESR2CYP17A1CYP19A1 | |
| SCHEMBL13376967 | 0.76 | CYP17A1 (0.40) | ESR1ESR2KMT2ANPSR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470513-B2 | Radiation-sensitive resin composition and polymer | JSR CORPORATION (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20120058429-A1 | RADIATION-SENSITIVE RESIN COMPOSITION AND POLYMER | JSR CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |