Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 7/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773011 | 1.00 | ADRB3 (0.59) | ADRB3CYP2D6MEN1SLC22A1KMT2A | |
| SCHEMBL9772953 | 0.87 | CYP2D6 (0.49) | ADRB3CYP2D6MEN1KMT2A | |
| SCHEMBL9772979 | 0.87 | CYP2D6 (0.49) | ADRB3CYP2D6MEN1KMT2A | |
| SCHEMBL9773081 | 0.82 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773077 | 0.82 | ADRB3 (0.58) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9773053 | 0.80 | ADRB3 (0.47) | ADRB3CYP2D6MEN1KMT2AADRB2 | |
| SCHEMBL9773045 | 0.80 | ADRB3 (0.47) | ADRB3CYP2D6MEN1KMT2AADRB2 | |
| SCHEMBL9769411 | 0.78 | ADRB3 (0.43) | ADRB3ADRB2ADRB1 | |
| SCHEMBL9769415 | 0.78 | ADRB2 (0.35) | ADRB3CYP2D6ADRB2ADRB1 | |
| SCHEMBL9769266 | 0.78 | ADRB2 (0.35) | ADRB3CYP2D6ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |