Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773053 | 1.00 | ADRB3 (0.47) | ADRB3ADRB1ADRB2HDAC3HDAC4 | |
| SCHEMBL9773081 | 0.91 | ADRB3 (0.58) | ADRB3ADRB1ADRB2HDAC3HDAC4 | |
| SCHEMBL9773077 | 0.91 | ADRB3 (0.58) | ADRB3ADRB1ADRB2HDAC3HDAC4 | |
| SCHEMBL10539205 | 0.82 | ADRB2 (0.50) | ADRB3ADRB1ADRB2ALDH1A1CYP1A2 | |
| SCHEMBL9773000 | 0.80 | ADRB3 (0.59) | ADRB3ADRB1ADRB2L3MBTL1CYP2D6 | |
| SCHEMBL9773011 | 0.80 | ADRB3 (0.59) | ADRB3ADRB1ADRB2L3MBTL1CYP2D6 | |
| SCHEMBL9773025 | 0.78 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6HTR2A | |
| SCHEMBL9773015 | 0.78 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6HTR2A | |
| SCHEMBL9773100 | 0.78 | ADRB3 (0.52) | ADRB3ADRB1ADRB2CYP2D6HTR2A | |
| SCHEMBL9772978 | 0.77 | ADRB3 (0.49) | ADRB3ADRB1ADRB2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030640-A | Alpha-heterocyclic ethanolamino alkylindoles, growth promoters and feed efficiency agents for animals, bronchodilators, antidepressants, antiobesity agents | MERCK & CO., INC. (US) | 1991-07-09 | — | — | US | disclosed |