Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788802 | 0.98 | LDHA (0.44) | LDHALMNATDP1PYCR1SLC6A4 | |
| SCHEMBL6223043 | 0.79 | LDHA (0.43) | LDHALMNATDP1PYCR1SLC6A4 | |
| SCHEMBL3821124 | 0.77 | TDP1 (0.44) | TDP1MAPTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2215535 | 0.77 | CYP1A2 (0.33) | MAPK1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2213115 | 0.77 | CYP1A2 (0.33) | KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4886698 | 0.76 | LDHA (0.40) | LDHALMNATDP1SLC6A4SLC6A2 | |
| SCHEMBL7929544 | 0.76 | CYP1A2 (0.34) | LMNAMAPTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL7015768 | 0.76 | MAOA (0.46) | LMNASLC6A4ALDH1A1MEN1KMT2A | |
| SCHEMBL2281906 | 0.75 | ALDH1A3 (0.52) | LDHALMNATDP1SLC6A4MAPT | |
| SCHEMBL8431691 | 0.75 | LDHA (0.50) | LDHALMNATDP1SLC6A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043332-A | Novel 11β-substituted -19-nor-steriods | ROUSSEL UCLAF (FR) | 1991-08-27 | — | — | US | disclosed |
| US-4978657-A | Antiprogesterones, antiglucocorticoids | ROUSSEL UCLAF (FR) | 1990-12-18 | — | — | US | disclosed |
| US-4634695-A | GLUCOCORTICOID INHIBITORS | ROUSSEL UCLAF (FR) | 1987-01-06 | — | — | US | disclosed |
| US-4519946-A | ANTIARTHRITIC, ANTIDIABETIC, ANTISECRETORY, AND HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1985-05-28 | — | — | US | disclosed |
| US-4447424-A | ANTIFERTILITY, ANTIINFLAMMATORY AGENT, HORMONE INHIBITOR | ROUSSEL UCLAF (FR) | 1984-05-08 | — | — | US | disclosed |
| US-4386085-A | ANTIGLUCOCORTICOIDS | ROUSSELL UCLAF (FR) | 1983-05-31 | — | — | US | disclosed |
| US-4206234-A | Triphenylbut-1-ene derivatives and pharmaceutical compositions and uses thereof | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |