Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9773810 | 0.84 | NPC1 (0.58) | MAPK14PLAUKMT2ANPC1RAB9A | |
| SCHEMBL9374793 | 0.81 | CYP26A1 (0.53) | MAPK14CYP1A2CYP2C9CYP2C19PLAU | |
| SCHEMBL19975477 | 0.80 | MAPK14 (0.57) | MAPK14CYP1A2CYP2C9CYP2C19RAF1 | |
| SCHEMBL10477924 | 0.78 | KMT2A (0.55) | MAPK14CYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL19975285 | 0.75 | MAPK14 (0.56) | MAPK14CYP1A2CYP2C9CYP2C19RAF1 | |
| SCHEMBL9773677 | 0.75 | IP6K1 (0.52) | MAPK14CYP1A2CYP2C9CYP2C19RAF1 | |
| SCHEMBL9375259 | 0.75 | RARB (0.55) | CYP1A2CYP2C9CYP2C19PLAUKMT2A | |
| SCHEMBL23143565 | 0.74 | TRPV1 (0.56) | PLAUNPC1RAB9A | |
| SCHEMBL9382115 | 0.73 | CYP26A1 (0.53) | CYP1A2CYP2C9CYP2C19PLAUKMT2A | |
| SCHEMBL9313889 | 0.71 | NPC1 (0.51) | MAPK14KMT2ANPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019587-A | Anticoagulants | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-28 | — | — | US | disclosed |