Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312812 | 0.94 | EPHX1 (0.53) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9866132 | 0.84 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9313210 | 0.81 | EPHX1 (0.51) | MAPTEPHX1HDAC1HDAC2MAPK14 | |
| SCHEMBL9312919 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9312531 | 0.74 | CNR1 (0.45) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9312934 | 0.74 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL9314257 | 0.73 | MAPT (0.49) | RAB9AMEN1MAPTKMT2AEPHX1 | |
| SCHEMBL9312900 | 0.73 | ALDH1A1 (0.54) | NPC1RAB9ASMN1; SMN2CNR1MEN1 | |
| SCHEMBL9312226 | 0.73 | MAPT (0.49) | RAB9ASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL9773752 | 0.71 | MAPK14 (0.55) | NPC1RAB9AMEN1KMT2AMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373019-A | Pharmaceutical lactam compositions for inhibition of erythrocyte and thrombocyte aggregation | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-13 | — | — | US | disclosed |
| US-4985448-A | Ureidoindoles, pharmaceutical compositions and methods for erythrocyte and thrombocyte aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-15 | — | — | US | disclosed |