Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969307 | 0.79 | KMT2A (0.33) | KMT2AMEN1ALDH1A1LMNATDP1 | |
| SCHEMBL8756239 | 0.77 | MEN1 (0.33) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9774507 | 0.76 | TSHR (0.39) | KMT2AMEN1TSHRHSD17B10KCNA5 | |
| SCHEMBL13623731 | 0.76 | TSHR (0.39) | KMT2AMEN1TSHRHSD17B10KCNA5 | |
| SCHEMBL16327200 | 0.75 | TSHR (0.37) | KMT2AMEN1LMNATSHRHSD17B10 | |
| SCHEMBL9300574 | 0.74 | TET2 (0.39) | KMT2AMEN1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL9774513 | 0.71 | CHRNB2 (0.42) | KMT2AMEN1TSHRHSD17B10KCNA5 | |
| SCHEMBL3186126 | 0.71 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL374306 | 0.71 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL161790 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985556-A | INTERMEDIATES | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) | 1991-01-15 | — | — | US | disclosed |