Toluene

Toluene

SCHEMBL9775158

CCN(CC)c1ccc(-c2nc(-c3cc(OC)c(O)c(OC)c3)n(C(=O)N=S(=O)=O)c2-c2ccc(N(CC)CC)cc2)cc1.Cc1ccccc1

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 4/20 0.38
NOX1 Q9Y5S8 1/20 0.36
TP53 P04637 2/20 0.35
MAPT P10636 2/20 0.35
GAA P10253 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
ESR1 P03372 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
HTT P42858 1/20 0.34
CASP7 P55210 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099285 0.84 SMPD3 (0.40) SMPD3NOX1TP53MAPTGAA
SCHEMBL10914827 0.80 SMPD3 (0.38) SMPD3TP53MAPTGAAKDM4E
SCHEMBL9683799 0.79 SMPD3 (0.37) SMPD3NOX1TP53MAPTGAA
SCHEMBL9683039 0.77 ALDH1A1 (0.39) SMPD3MAPTGAAKDM4EALDH1A1
SCHEMBL9684929 0.77 ALDH1A1 (0.36) SMPD3MAPTGAAKDM4EALDH1A1
SCHEMBL9494004 0.77 SMPD3 (0.40) SMPD3NOX1TP53MAPTGAA
SCHEMBL4087612 0.76 SMPD3 (0.37) SMPD3NOX1TP53MAPTGAA
SCHEMBL12152129 0.76 TEK (0.40) SMPD3NOX1TP53MAPTGAA
SCHEMBL10082740 0.74 SMPD3 (0.43) SMPD3NOX1TP53MAPT
SCHEMBL9683814 0.71 ALDH1A1 (0.38) SMPD3MAPTGAAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3024061-A None JP disclosed
JP-H0324061-A NOVEL OXIDIZABLE COLOR REAGENT WAKO PURE CHEM IND LTD 1991-02-01 JP disclosed